From what @GreggZ was saying it might just be a waste of energy to combine them in the first place, but this is good info to have. If the filters used .625" hose, using your formulas above, I would size up to 1" PVC, correct?I like your drawing @Jellopuddinpop
Now onto some some fluid dynamics, hopefully without getting to deep.
In your diagram above lets assume both canister filters are the same. They both use 1/2" ID hoses from the manufacturer.
A 1/2" hose has a cross section area of 0.19625 sq.in. (3.14*R2). Two 1/2" hoses would have a cross section area of 0.3925 sq.in.
If you "T" the two 1/2" hoses to a 3/4" pipe going up, The 3/4" pipe has a cross section area of 0.441563 sq.in.
So, as you can see, the single 3/4" pipe will offer a path of less resistance for the 2 filters than a single filter on it's own.
Path of least resistance... this is the part that needs to be better understood.
If the filter on the left stops working (assuming it is still full of water and the tank to filter return is still full of water...
The filter on the right will have a choice - try and push water backwards thru the 1/2" tube and into the filter full of water and mechanical filtration, or, go up the 3/4" pipe and out into the tank.
Generally speaking, the water output from the right filter is going to follow the path of least resistance and go up the 3/4" pipe and into the tank.
In designing the horizontal spray bar - it should be noted that the sum of all the spray bar holes should be equal to or greater than the cross section area of the 3/4" riser pipe. This way, the spray bar itself will not add resistance to the flow of water. Each horizontal pipe in the spray bar can be 1/2" pipe without drastically effecting water flow - assuming the above sentence if followed. 3/4" horizontal pipes would be my overall preference.
Even with identical filters (which I would need to get), they're still not going to have the same flow. The one pushing the reactor has a lot of fittings to contend with, and the one running the inline heater has... well... an inline heater. If we assume for a minute that one filter has more head pressure than the other, and thus less flow, what happens then?
Does the stronger filter push against the weaker one, restricting flow even more?